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干花豆抗衰老有效部位的研究(PDF)

《广西植物》[ISSN:1000-3142/CN:45-1134/Q]

期数:
2014年05期
页码:
723
栏目:
研究简报
出版日期:
2014-09-10

文章信息/Info

Title:
Protective effects of fordia cauliflora hemsl on the D-galactose induced senile dementia model mice
文章编号:
1000-3142(2014)05-0723-04
作者:
杨子明 刘金磊* 颜小捷 李典鹏
广西植物功能物质研究与利用重点实验室, 广西植物研究所, 广西 桂林 541006
Author(s):
YANG Zi-Ming LIU Jin-Lei* YAN Xiao-Jie LI Dian-Peng
Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guilin 541006, China
关键词:
老年性痴呆症小鼠 学习记忆能力 潜伏时间 超氧化物歧化酶 丙二醛
Keywords:
aging mice ability of learning and memory latency SOD MDA
分类号:
Q946; R285.5
DOI:
10.3969/j.issn.1000-3142.2014.05.026
文献标识码:
A
摘要:
采用小鼠避暗行为学实验测定干花豆对老年痴呆小鼠记忆能力的影响,通过测定血液中的甘油三酯、总胆固醇及血液和大脑中的抗氧化指标来评价干花豆抗衰老作用。结果表明:干花豆各剂量组均能降低血脂水平,提高抗氧化能力,其中粗提物和正丁醇组有改善记忆力的作用,说明干花豆抗衰老的有效部位可能在正丁醇提取部位。
Abstract:
KM Alzheimier’s disease mice models caused by D-galactose,the abilities of learning and memory of mice were investigated by avoid dark experiment in all animals,and antioxidant were used to study protective effects of fordia cauliflora hemsl on the D-galactose induced senile dementia model mice. Fordia cauliflora hemsl could increased antioxidant and decreased lipids,but the results suggested that fordia cauliflora hemsl and fordia cauliflora hemsl butanol extract might be beneficial to inproving the learning and memory behaviors in mice with Alzhemiers’ disease induced by D-galactose. The results of pharmacological experiment results confirmed that the active part of fordia cauliflora hemsl butanol extract.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期: 2013-12-17修回日期: 2014-03-10
基金项目: 广西科技攻关项目(桂科攻1140001-36); 桂林市科技开发项目(20110107-2); 广西植物研究所基本业务费项目(桂植业09034); 广西植物功能物质研究与利用重点实验室主任基金(ZRJJ2013-6)。
作者简介: 杨子明(1982-),男,广西兴安县人,硕士研究生,助理研究员,从事植物活性物开发与利用研究,(E-mail)yangziming198310@126.com。 *通讯作者: 刘金磊,副研究员,从事植物活性物开发与利用研究,(E-mail)liujinlei@126.com。
更新日期/Last Update: 2014-09-10